Following is a list of recent publications from the Glenn King Lab at UConn Health Center. Links to PubMed abstracts and Journal download sites are provided where available.


2004 Publications


  1. Rowland, S.L., Burkholder, W.F., Cunningham, K.A., Maciejewski, M.W., Grossman, A.D., and King, G.F. (2004) Structure and mechanism of Sda, an inhibitor of the histidine kinases that regulate initiation of sporulation in Bacillus subtilis. Molecular Cell 13, 689-701.
    PubMed | Journal

  2. Tedford, H.W., Gilles, N., Ménez, A., Doering, C.J., Zamponi, G.W., and King, G.F. (2004) Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against invertebrate calcium channels. Journal of Biological Chemistry 279, 44133-44140.
    PubMed | Journal

  3. King, G.F. (2004) The wonderful world of spiders: preface to the special Toxicon issue on spider venoms. Toxicon 43, 471-475. (Editorial)
    PubMed | Journal

  4. Tedford, H.W., Sollod, B.L., Maggio, F., and King, G.F. (2004) Australian funnel-web spiders: master insecticide chemists. Toxicon 43, 601-618. (Review)
    PubMed | Journal

  5. Sollod, B.L., Wilson, D., Zhaxybayeva, O., Gogarten, J.P., Drinkwater, R., and King, G.F. (2004) Were arachnids the first to use combinatorial peptide libraries? Peptides 25, in press.
    PubMed | Journal

  6. Ma, L., King, G.F., and Rothfield, L.I. (2004) Positioning of MinE and MinC binding sites on the MinD surface provides a mechanism for activation of the E. coli MinD ATPase during division site selection. Molecular Microbiology 54, 99-108.
    PubMed | Journal

  7. Doley, R., King, G.F., and Mukherjee, A.K. (2004) Differential hydrolysis of erythrocyte and mitochondrial membrane phospholipids by two phospholipase A2 isoenzymes (NK-PLA2-I and NK-PLA2-II) from the venom of the Indian monocled cobra Naja kaouthia. Archives of Biochemistry and Biophysics 425, 1-13.
    PubMed | Journal

  8. Maggio, F., Sollod, B.L., Tedford, H.W., and King, G.F. (2004) Spider toxins and their potential for insect control. In: Comprehensive Molecular Insect Science (Gilbert, L.I., Iatrou, K., and Gill, S.S., eds), Volume 5, Chapter 5.7, pp. 221-238, Elsevier. (Book chapter, ISBN 0-44-451516-X)
    Publisher site

  9. Maciejewski, M.W., Stern, A.S., King, G.F., and Hoch, J.C. (2004) Nonuniform sampling in biomolecular NMR. In: Handbook of Modern Magnetic Resonance (Webb, G.A., ed.), Kluwer Academic Publishers, London, in press. (Book chapter)

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2003 Publications


  1. Szeto, T.H., Rowland, S.L., Habrukowich, C.L., and King, G.F. (2003) The MinD membrane targeting sequence is a transplantable lipid-binding helix. Journal of Biological Chemistry 278, 40050-40056.
    PubMed | Journal

  2. Ma, L., King, G.F., and Rothfield, L.I. (2003) Mapping the MinE site involved in interaction with the MinD division site placement protein of Escherichia coli. Journal of Bacteriology 185, 4948-4955.
    PubMed | Journal

  3. Guss, J.M., and King, G.F. (2003) Macromolecular structure determination: comparison of crystallography and NMR. In: Encyclopedia of the Human Genome, Macmillan, London. (Book chapter).
    Online Publisher Site

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2002 Publications


  1. Szeto, T.H., Rowland, S.L., Rothfield, L.I. and King, G.F. (2002) Membrane localization of MinD is mediated by a C-terminal motif that is conserved across eubacteria, archaea, and chloroplasts. Proceedings of the National Academy of Sciences USA 99, 15693-15698.
    PubMed | Journal

  2. Shih, Y.-L., Fu, X., King, G.F., Le, T. and Rothfield, L.I. (2002) Division-site placement in E. coli: mutants that prevent formation of the MinE ring lead to loss of the normal midcell arrest of growth of polar MinD membrane domains. EMBO Journal 21, 3347-3357.
    PubMed | Journal

  3. Maggio, F. and King, G.F. (2002) Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function. Journal of Biological Chemistry 277, 22806-22813.
    PubMed | Journal

  4. Boysen, R.I., Jong, A.J.O., Wilce, J.A., King, G.F., and Hearn, M.T.W. (2002) Role of interfacial hydrophobic residues in the stabilization of the leucine zipper structures of the transcription factors c-Fos and c-Jun. Journal of Biological Chemistry 277, 23-31.
    PubMed | Journal

  5. Robson, S.A., Michie, K.A., Mackay J.P., Harry, E. and King, G.F. (2002) The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components. Molecular Microbiology 44, 663-674.
    PubMed | Journal

  6. King, G.F., Tedford, H.W. and Maggio, F. (2002) Structure and function of insecticidal neurotoxins from Australian funnel-web spiders. Journal of Toxicology - Toxin Reviews 21, 361-389. (Review)
    PubMed | Journal

  7. Bains, N.P., Gorbatyuk, V.Ya., Nosworthy, N.J., Robson, S.A., Maciejewski, M.W., dos Remedios, C.G. and King, G.F. (2002) Backbone and side-chain 1H, 15N, and 13C assignments for chick cofilin. Journal of Biomolecular NMR 22, 193-194.
    PubMed | Journal

  8. Maggio, F. and King, G.F. (2002) Role of the structurally disordered N- and C-terminal residues in the Janus-faced atracotoxins. Toxicon 40, 1355-1361.
    PubMed | Journal

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2001 Publications


  1. Rothfield, L.I., Shih, Y.-L., and King, G.F. (2001) Polar explorers: membrane proteins that determine division site placement. Cell 106, 13-16. (Review)
    PubMed | Journal

  2. Szeto, T.H. , Rowland, S.L. and King, G.F. (2001) The dimerization function of MinC residues in a structurally autonomous C-terminal domain. Journal of Bacteriology 183, 6684-6687.
    PubMed | Journal | Front Cover

  3. Tedford, H.W., Fletcher, J.I. and King, G.F. (2001) Functional significance of the ß hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a. Journal of Biological Chemistry 276, 26568-26576.
    PubMed | Journal

  4. Wang, X-H., Connor, M., Wilson, D., Wilson, H.I., Nicholson, G.M., Smith, R., Shaw, D., Mackay, J.P., Alewood, P.F., Christie, M.J. and King, G.F. (2001) Discovery and structure of a potent and highly specific blocker of insect calcium channels. Journal of Biological Chemistry 276, 40306-40312.
    PubMed | Journal

  5. Blair, D.H., Lin, Y.Q., Robson, S.A., King, G.F., and Bennett, M.R. (2001) Vesicle-associated proteins and transmitter release from sympathetic ganglionic boutons. Neuroreport 12, 607-610.
    PubMed | Journal

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2000 Publications


  1. King, G.F., Shih, Y.-L., Maciejewski, M.W., Bains, N.P.S., Pan, B., Rowland, S.L., Mullen, G.P. and Rothfield, L.I. (2000) Structural basis for the topological specificity function of MinE. Nature Structural Biology 7, 1013-1017.
    PubMed | Journal | News & Views

  2. Wang, X-H., Connor, M., Smith, R., Maciejewski, M.W., Howden, M.E.H., Nicholson, G. M., Christie, M. J. and King, G. F. (2000) Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bond. Nature Structural Biology 7, 505-513.
    PubMed | Journal

  3. Szeto, T.H., Birinyi-Strachan, L.C., Smith, R., Connor, M., Christie, M.J., King, G.F., and Nicholson, G.M. (2000) Isolation and pharmacological characterisation of delta-atracotoxin-Hv1b, a vertebrate-selective sodium channel toxin. FEBS Letters 470, 293-299.
    PubMed | Journal

  4. Szeto, T.H., Wang, X.-H., Smith, R., Connor, M., Christie, M.J., Nicholson, G.M., and King, G.F. (2000) Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1. Toxicon 38, 429-442.
    PubMed | Journal

  5. Wilce, J.A., Wake, R.G., and King, G.F. (2000) Termination of replication in bacteria. In: Encyclopedia of Life Sciences, Macmillan, London. (Book chapter)
    Publisher site

  6. Guss, J.M., and King, G.F. (2000) Macromolecular structure determination: comparison of crystallography and NMR. In: Encyclopedia of Life Sciences, Macmillan, London. (Book chapter)
    Publisher site

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1999 Publications


  1. King, G.F., Rowland, S.L., Pan, B., Mackay, J.P., Mullen, G.P. and Rothfield, L.I. (1999) The dimerization and topological specificity functions of MinE reside in a structurally autonomous C-terminal domain. Molecular Microbiology 31, 1161-1170.
    PubMed | Journal

  2. Duggin, I.G., Andersen, P.A., Smith, M.T., Wilce, J.A., King, G.F., and Wake, R.G. (1999) Site-directed mutants of RTP of Bacillus subtilis and the mechanism of replication fork arrest. Journal of Molecular Biology 286, 1325-1335.
    PubMed | Journal

  3. Bains, N.P.S., Wilce, J.A., and King, G.F. (1999) Controlling leucine zipper specificity with interfacial hydrophobic residues. Letters in Peptide Science 6, 381-390.
    PubMed | Journal

  4. Wang, X.-H., Smith, R., Fletcher, J.I., Wilson, H., Wood, C.J., Howden, M.E.H., and King, G.F. (1999) Structure-function studies of omega-atracotoxin, a potent antagonist of insect voltage-gated calcium channels. European Journal of Biochemistry 264, 488-494.
    PubMed | Journal

  5. Fletcher, J.I., Dingley, A.D., Smith, R., Connor, M., Christie, M.J., and King, G.F. (1999) High-resolution structure of gurmarin, a sweet-taste suppressing plant polypeptide. European Journal of Biochemistry 264, 525-533.
    PubMed | Journal

  6. Torres, A.M., Wang, X., Fletcher, J.I., Alewood, D., Alewood, P.F., Smith, R., Simpson, R., Nicholson, G.M., Sutherland, S.K., Gallagher, C.H., King, G.F., and Kuchel, P.W. (1999) Solution structure of a defensin-like peptide from platypus venom. Biochemical Journal 341, 785-794.
    PubMed | Journal

  7. Kowalski, K., Czolij, R., King, G.F., Crossley, M., and Mackay, J.P. (1999) The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. Journal of Biomolecular NMR 13, 249-261.
    PubMed | Journal

  8. King, G.F., Pan, B., Maciejewski, M.W., Rowland, S.L., Rothfield, L.I. and Mullen, G.P. (1999) Backbone and side-chain 1H, 15N, and 13C assignments for the topological specificity domain of the MinE cell division protein. Journal of Biomolecular NMR 13, 395-396.
    PubMed | Journal

  9. Fletcher, J.I., Wang, X., Connor, M., Christie, M.J., King, G.F., and Nicholson, G.M. (1999) Spider toxins: a new group of potassium channel modulators. In: Perspectives in drug discovery and design: animal toxins and potassium channels (Darbon, H. and Sabatier, J.-M., eds), Volume 15/16, pp. 61-69, Kluwer/Escom, Dordrecht. (Book chapter)
    Publisher site

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