SuperQuick Links: ExPASY NCBIPDBDALIBMRBPfamiPfam ProDomTIGRSangerSigPCOGsSBTools


Protein/DNA sequence analysis

Clusters of Orthologous Groups (COGS). Quick Links: Home • COGS of bacterial cell division and cell envelope biogenesis proteins.

Pfam database of protein domains and families. Quick Links: HomeProtein or DNA search • iPfam domain interaction database.

National Center for Biotechnology Information. Quick Links: HomePubMedGenome PageBLAST • BLAST Microbial and Human Genomes

The Sanger Institute. Quick Links: HomeHuman and C. elegans BLAST • Microbial and Protozoan GenomesEnsembl Browser

Expert Protein Analysis System of the Swiss Institute of Bioinformatics. Quick Links: HomeSWISS-PROT/TrEMBLPROSITETox-ProtCalculate MW/pISWISS-MODEL

The Institute for Genomics Research (TIGR). Quick Links: HomeCompleted & Unfinished Microbial Genomes • TIGR Software

SignalP predicts the location of signal peptide cleavage sites in protein sequences from prokaryotes and eukaryotes.

ProDom is an automatic compilation of homologous protein domains. BLAST your sequence against the ProDom database.


Protein structural analysis

The Protein Data Bank is the international repository for biomacromolecular structures. Link to the home page, do a text search of PDB entries, check the status of unreleased entries, or deposit coordinates.

The DALI server searches the PDB for structural homologs of a protein. Go to the FSSP database to view structural neighbours of proteins already in the PDB.

The MultiCoil program predicts the location of coiled-coil regions in amino acid sequences and classifies whether the coils are likely to be dimeric or trimeric.

The PredictProtein server finds homologs of a protein sequence, detects functional motifs and domains, and predicts secondary structure based on a single sequence or multiple sequence alignment.


NMR sites

BioMagResBank is the international repository for NMR data from biomacromolecules. Quick Links: Retrieve dataDeposit dataDownload pulse sequencesView average chemical shifts.

Kurt Wüthrich shared the 2002 Nobel Prize in Chemistry for his pioneering NMR studies on protein structure. Check out some of the software developed in his lab.

The Structural Biology Tools server at UConn Health Center provides automated Felix and NMRPipe macro generators, as well as online programs for viewing apodization functions.

The NMR Information server provides a list of worldwide NMR facilities, NMR groups, NMR meetings, and NMR jobs.


Links to Bacteria/Plastid Cell Division Labs

Jon Beckwith, Department of Microbiology and Molecular Genetics, Harvard Medical School, USA

Piet de Boer, Department of Molecular Biology and Biochemistry, Case Western Reserve University, USA

Yves Brun, Department of Biology, Indiana University, USA

Harold Erickson, Department of Cell Biology, Duke University Medical Center, USA

Jeff Errington, Sir William Dunn School of Pathology, University of Oxford, UK

Alan Grossman, Department of Biology, Massachusetts Institute of Biology, USA

Frederico Gueiros-Filho, Departamento de Bioquímica, Instituto de Química, Brazil

Liz Harry, Department of Biochemistry, University of Sydney, Australia

Glenn King, Department of Biochemistry, UConn Health Center, USA

Petra Levin, Department of Biology, Washington University, USA

Richard Losick, Department of Molecular and Cellular Biology, Harvard University, USA

Jan Löwe, MRC Laboratory of Molecular Biology, Cambridge, UK

Joe Lutkenhaus, Department of Microbiology, Molecular Genetics and Immunology, Univ. of Kansas Medical Center, USA

William Margolin, Department of Microbiology and Molecular Genetics, University of Texas, USA

Katherine Osteryoung, Department of Biochemistry, University of Nevada, USA

Larry Rothfield, Department of Microbiology, UConn Health Center, USA

Miguel Vicente, Centro Nacional de Biotecnologia, Spain

David Weiss, Department of Microbiology, University of Iowa, USA

Andrew White, Sackler School of Biomedical Sciences, Tufts University, USA


Links to Biopesticide/Insect Toxin Research Labs

Michael Adams, Departments of Neuroscience and Entomology, University of California Riverside, USA

Biotechnology Program, Department of Entomology, Commonwealth Scientific and Industrial Research Organization, Australia

Nor Chejanovsky, Department of Entomology, Agricultural Research Organization, Israel

Michael Gurevitz, Department of Plant Sciences, Tel Aviv University, Israel

Bruce Hammock, Department of Entomology, University of California Davis, USA

Glenn King, Department of Biochemistry, UConn Health Center, USA

Graham Nicholson, Department of Health Sciences, University of Technology Sydney, Australia

Eliahu Zlotkin , Department of Cell and Animal Biology, Alexander Silberman Institute of Life Sciences, Israel


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